Liquid Handler

Liquid Handlers: Tecan: Freedom EVO 100 MCA Building on over 20 years of experience in providing versatile liquid handling platforms for the Life Sciences, the Freedom EVO platform delivers even more flexibility and possibilities for expansion according to future needs. Together with the new easy-to-use software, Freedom EVOware, each system is equipped to successfully operate genomics, proteomics, and drug discovery applications. Now all laboratory personnel have access to a platform that will grow and change with their application needs. With Freedom EVO you choose the freedom to evolve. Genomics Nucleic acid extraction by solid phase extraction (SPE), magnetic bead separation or centrifugation Sequencing reaction set-up PCR set-up PCR PCR clean-up Genotyping single nucleotide polymorphism (SNP) scoring Spot array printing, hybridization, and DNA normalization Gene expression in situ hybridization (ISH), fluorescence in situ hybridization (FISH), immunohistochemistry (IHC) applications Proteomics Protein digestion and MALDI spotting Protein crystallization and crystallization set-up Protein solubility Recombinant protein purification Drug Discovery Compound synthesis Compound weighing and dilution High throughput screening (HTS), ultrahigh throughput screening (UHTS) & secondary screening Toxicity assays Compound management Hit picking and plate reformatting Cell culture and cell maintenance Sample preparation for flow cytometry Compound characterization Plate replication Compound stability Automated assays for Absorption, Distribution, Metabolism, Excretion, Toxicity (ADMET) include: Micosome and hepatocyte metabolic stability assays Cell permeability studies Blood brain barrier permeability Skin permeability Eye irritation Compound solubility Cytochrome P450 inhibition Cell migration, invasion assays Metabolite identification CYP450 induction CYP450 isoform identification Serum protein binding Other Applications Multifunctional plate reading Multichannel pipetting